产品货号：
Z11836
中文名称：
BAFF/TNFSF13B抗体
英文名称：
Anti-BAFF/TNFSF13B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BAFF/TNFSF13B Antibody |
| 指标别名 | TNF superfamily member 13b;BAFF;BLYS;CD257;DTL;TALL-1;TALL1;THANK;TNFSF20;TNLG7A;ZTNF4;TNFSF13B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | TNFSF13B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human BAFF(265-285aa RENAQISLDGDVTFFGALKLL),different from the related rat and mouse sequences by three amino acids. |
| 实际分子量 | 31KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BAFF was regularly detected by enzyme-linked immunosorbent assay in brain tissue lysates and in normal spinal fluid,and in astrocytes by double fluorescence microscopy.BAFF was localized in astrocytes close to BAFF-R-expressing immune cells.BAFF receptors were strongly expressed in situ in primary central nervous system(CNS) lymphomas.The TNF superfamily member B cell-activating factor(BAFF) plays an important role in humoral immunity and in autoimmune diseases,including RA.Local BAFF gene targeting inhibited proinflammatory cytokine expression,suppressed generation of plasma cells and Th17 cells,and markedly ameliorated joint pathology.The B cell activating factor BAFF(BlyS/TALL-1/zTNF4) is a tumor necrosis factor(TNF)-related ligand that promotes B cell survival and binds to three receptors(BCMA,TACI,and the recently described BAFF-R).Human BAFF was mapped to chromosome 13q32-34.4.The standard used in this kit is recombinant soluble human BAFF(A134-L295) with the molecular mass of 19.6KDa. |
| Uniprot ID | Q9Y275 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | tumor necrosis factor(ligand) superfamily,member 13b |
| 蛋白名全称 | Tumor necrosis factor ligand superfamily member 13B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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